7月15日 据欧联社综合报道,周二(14日)发布在《自然-通讯》科学期刊一项研究报告,法国一名女子怀孕时确诊新冠病毒,胎儿出生后出现相关症状,其后证实感染。医生认为胎儿在母体内经胎盘感染,是全球首例证实的胎儿在子宫内被感染。

研究报告由巴黎安托万•贝克莱尔(Antoine Béclère)医院儿科与新生儿重症护理医学主任丹妮尔•德•卢卡(Daniele De Luca)撰写,一名23岁女子在怀孕35周时、即今年3月24日因发烧及咳嗽而入院,确认检验结果为感染新冠病毒。该孕妇入院3天后,医生发现胎儿出现疼痛迹象,因此研究团队在完全隔离和全身麻醉下对该孕妇实施了剖宫产术,羊膜完好。剖宫产时,研究团队在破膜前收集了清澈的羊水,期间杜绝一切病毒源头。

男婴出生后,医院从婴儿的肺部抽出血液与其他体液,确诊婴儿感染新冠病毒,并排除了其他病毒等细菌感染。医生进一步检查后显示,病毒从母亲的血液传到胎盘,而使婴儿被感染。报告指他起初看来健康,但3天后情况突然转差,不但变得易怒,更出现肌肉痉挛及僵直,脑膜炎,脑水肿等与新冠病毒相关的症状,喂食亦有困难,男婴一度连接呼吸机6小时。

权威杂志《柳叶刀》:初步证明新冠病毒不会母婴垂直

医院当时没有关于如何治疗确诊婴儿的临床指引,医生曾考虑是否使用瑞德西韦,但男婴在没有帮助的状况下逐渐康复,因此并未获得特定药物。最近对其扫描结果显示,他身体已几乎完全康复,并在3周内出院,他的母亲3个月后再无病征。

丹妮尔•德•卢卡的团队进一步研究后发现,胎盘内的病毒浓度最高,认为是由母体经血液及脐带传染给胎儿。他表示,之前无法证明胎儿在母体内受感染,是因为在疫情大流行下,难以全面分析羊水,胎盘,婴儿血液等来确认胎盘的病理学。

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